The global bone grafts & substitutes market size was US$ 2.7 billion in 2021. The global bone grafts & substitutes market size is forecast to reach US$ 3.7 billion by 2030, growing at a compound annual growth rate (CAGR) of 4.6% during the forecast period from 2022 to 2030.

Bone grafts are implantable materials with osteoconductive, osteogenic, and osteoinductive qualities. In addition, it facilitates bone healing, bone production, and osseous reconstruction. Sports, trauma, plastic, facial, and spinal operations all use them. They can also utilize to fill cavities in the absence of bones or aid in providing structural support. Bone grafting is a surgical treatment that involves using a substance (bone graft) from a patient's own body, a cadaver, an animal, or a different person to replace a missing or defective bone. It helps for wound healing, difficult fracture therapy, and other things.

Factors Influencing Market Growth

The growing incidence of musculoskeletal disorders, the expansion of biocompatible synthetic bone grafts, and technical advancements in the medical field directing to a shift from autograft to allograft and a surge in demand for dental bone grafts are factors driving the global market.
Rising costs of surgeries and ethical problems related to bone grafting procedures may slow down the overall market growth.
The rising focus of key players on R&D activities in bone grafts & their substitutes and the growing demand for orthopedic procedures among the elderly population is forecast to provide lucrative opportunities for the global market during the forecast period.
Impact Analysis of COVID-19

The COVID-19 pandemic had a negative impact on the medical device companies in the bone grafts & substitutes industry. Leading Companies faced a setback due to the lockdown imposed by the government, which has led to disturbances in the supply chain movements globally. In addition, prominent players faced issues concerning the availability of human resource for manufacturing bone grafts & substitutes at production facilities. Additionally, end-users such as hospitals and clinics reported declining inpatient visits due to the lockdown restrictions.

Regional Insights

North America garnered the maximum share in the market in 2021 and is forecast to maintain its position over the forecast period. As a result of the rising awareness associated with the commercially available innovative products, accessibility of well-developed healthcare infrastructure, and higher healthcare expenses. The market in the U.S. is leading North America by developing the highest demand for bone grafts and substitutes owing to the increasing number of trauma-related injuries and cases of orthopedic disease. Thus, these factors are forecast to fuel the market growth in the region.

Leading Competitors

The leading prominent companies profiled in the global bone grafts & substitutes market are:

Arthrex, Inc.
Baxter International Inc.
Johnson & Johnson (DePuy Synthes)
Medtronic Plc.
Integra LifeSciences Holdings Corporation
Musculoskeletal Transplant Foundation
NuVasive, Inc.
Stryker Corporation
Xtant Medical Holdings, Inc.
Zimmer Biomet Holdings, Inc.
Other Prominent Players
Scope of the Report

The global bone grafts & substitutes market segmentation focuses on Product, Application, and Region.

Segmentation based on Product

Allografts
Machined Allografts
Demineralized Bone Matrix
Bone Grafts Substitutes
Bone Morphogenic Proteins (BMP)
Synthetic Bone Grafts
Cell-Based Matrices
Segmentation based on Application

Spinal Fusion
Trauma
Craniomaxillofacial
Joint Reconstruction
Dental Bone Grafting
Segmentation based on Region

North America
The U.S.
Canada
Mexico
Europe
Western Europe
The UK
Germany
France
Italy
Spain
Rest of Western Europe
Eastern Europe
Poland
Russia
Rest of Eastern Europe
Asia Pacific
China
India
Japan
Australia & New Zealand
ASEAN
Rest of Asia Pacific
Middle East & Africa (MEA)
UAE
Saudi Arabia
South Africa
Rest of MEA
South America
Brazil
Argentina
Rest of South America